＜p＞Genetic effects are the core concepts from which quantitative genetics and the evolutionary synthesis emerged. The groundbreaking theory of genetic effects was first proposed over a century ago. This book revises that theory, both conceptually and mathematically, and brings it up-to-date.＜/p＞
＜ul＞
＜li＞The theory here compiled is supplemented with non-previously-published developments covering the broadest spectrum of simultaneously multiallelic and multilocus architectures with autosomal and sex-linked loci＜/li＞
＜li＞Arbitrary interactions (dominance, gene-gene, gene-environment, gene-sex, and parent-of-origin interactions) are accounted for＜/li＞
＜li＞Both effects of allele substitutions from the reference of individual genotypes and in the context of populations are worked out＜/li＞
＜li＞Populations are considered regardless of any departures from equilibrium frequencies (including both departures from Hardy-Weinberg, departures from linkage equilibrium, and non-random associationsbetween/among genes and environments)＜/li＞
＜li＞All developments are derived under the same mathematical framework, so that transformations of genetic effects between different contexts are easily allowed＜/li＞
＜/ul＞
＜p＞In brief, this book enables novel applications to current empirical paradigms (like gene-mapping and genomic prediction) while adhering to the classical conceptualization of genetic effects and variance decomposition that let quantitative genetics and the evolutionary synthesis flourish.＜/p＞
＜p＞All relevant concepts are carefully clarified and discussed from a historical perspective. The theoretical developments presented in the book are illustrated by built-in cases and applications with real data. Reassuringly, the adequacy of the theory here presented is corroborated based on the fundamentals of model development.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。

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